Expert Rev Anti Infect Ther. HHS UV also reversed cytokine production and blocked cytokine release.  |  Get the latest research from NIH: All the dogs that were treated with the optimized dose of UV to the blood, recovered from an overwhelming infection (while many dogs in the control group died). Ultraviolet C, Knott hemo-irradiator, UBI, DNA repair, Blood cells, Antigen-presenting cells, Infections, Cytokines, Firstly, PCR is an amplification tool, it can’t de…, Benford's law is not a law of physics hat cannot b…, its going to take much longer than the paltry coup…, Trump didn't follow Benfords law either, it looked…, So it can't be a science response unless it answer…, These findings seem to assume that gravity is cons…, Nov 7, 2020 Healthcare Worker Exposes Real Covid-1…, Nov 9, 2020 The Covid Cult | Thomas E. Woods, Jr.…, November 4, 2020 Wind and solar energy are ruining…, Copernicus Meets the Greenhouse Effect (PDF), Absence Of A Measurable Greenhouse Effect, Greenhouse Effect Theory Within the UN IPCC, Why CO2 Has Nothing To Do With Temperature, The Planck Blackbody Equation and Atmospheric Radiative Transfer, Finite Element Model for Atmospheric IR-Absorption, One-way heat flow formulation with Planck absorption and re-emission, Alternative Theory To Man-Made CO2’s Influence On Climate, Keynesian Economics’ Relationship To Economic Prolems. None of the dogs that were treated and survived, showed any long-term ill effects after 4 months of observation [7]. Rezaie A, Leite GGS, Melmed GY, Mathur R, Villanueva-Millan MJ, Parodi G, Sin J, Germano JF, Morales W, Weitsman S, Kim SY, Park JH, Sakhaie S, Pimentel M. PLoS One. Ichiki et al. We will be in touch about appointment times and dates. Ultraviolet A light effectively reduces bacteria and viruses including coronavirus. doi: 10.1371/journal.pone.0236199. Treating only 35 cc of blood with UBI induces a beneficial systemic response. Kabat proved that UV-irradiation could affect the osmotic properties of red blood cells, the submicroscopic structure and the metabolism of adenine nucleotides. However there are differences between UBI and ECP in that UBI tends to stimulate the immune system, while ECP tends to be immunosuppressive. Principia Scientific International (PSI) is a not-for-profit community interest association. However the use of UBI to treat septicemia cannot be solely due to UV-mediated killing of bacteria in the blood-stream, as only 5–7{154653b9ea5f83bbbf00f55de12e21cba2da5b4b158a426ee0e27ae0c1b44117} of blood volume needs to be treated with UV to produce the optimum benefit. However an excessive dose of UV could decrease the production of H2O2 [37]. Head Office: 27 Old Gloucester Street, London WC1N 3AX. The oxidative nature of UBI may have mechanisms in common with ozone therapy and other oxygen therapies. No resistance of microorganisms to UV irradiation has been reported, and multi- antibiotic resistant strains are as susceptible as their wild-type counterparts. Clin Rev Allergy Immunol. Please let us know what type of health issues that you would like to address or questions that you might have. Is Sustainable Energy Even Possible Globally? They found that it was unnecessary to deliver a sufficient exposure of UV light to the blood to directory kill all the bacteria in the circulation. Antigen-presenting cells; Blood cells; Cytokines; DNA repair; Infections; Knott hemo-irradiator; UBI; Ultraviolet C. Comparison of DNA damage produced by ( a ) UVB or UVC (intra-strand…, NLM A two-phase polymer system containing poly-dextran was used to show that the cell surface of circulating erythrocytes was reduced after UV irradiation. No resistance of microorganisms to UV irradiation has been reported, and multi-antibiotic resistant strains are as susceptible as their wild-type counterparts. Trace UV from sunlight has been demonized when sun-blocking heavy metal creams seems more likely to cause skin cancers and inflammation. Confusion has been caused by the widely held idea that since UV is used for sterilization of water and surgical instruments; therefore its use against infection must also rely on UV-mediated direct destruction of pathogens. In 1855, Rikli from Switzerland opened a thermal station in Veldes in Slovenia for the provision of helio-therapy [3]. Clin Exp Dermatol. COVID-19 is an emerging, rapidly evolving situation. Liebert A, Bicknell B, Johnstone DM, Gordon LC, Kiat H, Hamblin MR. Photobiomodul Photomed Laser Surg. UBI may enhance the phagocytic capacity of various phagocytic cells (neutrophils and dendritic cells), inhibit lymphocytes, and oxidize blood lipids. Online ahead of print. The UBI irradiates the blood with ultraviolet (UV) light (specifically UVA & UVC wavelengths), which has broad-acting effects, like increasing red and white blood cells, hemoglobin, blood alkalinity, phagocytosis capability, the bactericidal capacity of the blood, immune system modulation, and much more. Low and mild doses of UV kill microorganisms by damaging the DNA, while any DNA damage in host cells can be rapidly repaired by DNA repair enzymes. Twenty-nine different conditions were described as being responsive, including the following: infectious arthritis, septic abortion, osteoarthritis, tuberculosis glands, chronic blepharitis, mastoiditis, uveitis, furunculosis, chronic paranasal sinusitis, acne vulgaris, and secondary anemia [23, 24]. 2019 Nov;37(11):681-693. doi: 10.1089/photob.2019.4628. Hancock and Knott [8] had similar success in another patient suffering from advanced hemolytic streptococcal septicemia. The early studies were carried out by several physicians in USA and published in the American Journal of Surgery. GRAVISPHERES: What’s the matter with Dark Matter? The irradiation chamber was circular and contained a labyrinthine set of channels that connected the inlet and outlet ports. A shortening of the time of hospitalizations and accelerated convalescence was regularly observed. Our goal is to remind people to continue to do more research and explore more clinical uses. Post was not sent - check your email addresses! With his collaborator Edblom, an irradiation chamber was constructed to allow direct exposure of the blood to UV. Back Radiation Greenhouse Effect of 33 Kelvin Possible? 2020 Jul 16;15(7):e0236199. 25.2). Ultraviolet Blood Irradiation (UBI) A safe and natural therapy using light as a natural antibiotic. Walter H Ude reported a series of 100 cases of erysipelas (a cutaneous infection caused by Streptococcus pyogenes) in the 1920s, with high cure rates using irradiation of the skin with UV light [6]. | #. He had a success rate of 98{154653b9ea5f83bbbf00f55de12e21cba2da5b4b158a426ee0e27ae0c1b44117} in thousands of cases, mostly the form of cutaneous tuberculosis known as lupus vulgaris [5]. It was also found unnecessary to expose the total blood volume in the dogs. UV radiation is divided into four distinct spectral areas including vacuum UV (100–200 nm), UVC (200–280 nm), UVB (280–315 nm) and UVA (315–400 nm). In a series of 75 cases in which the diagnoses of pneumonia were confirmed by X-rays, all patients responded well to UBI showing a rapid decrease in temperature, disappearance of cyanosis (often within 3–5 min), cessation of delirium if present, a marked reduction in pulse rate and a rapid resolution of pulmonary consolidation. [34] studied varying UV irradiation conditions on both red blood cells and leucocyte-thrombocyte suspensions. The early studies were carried out by several physicians in USA and published in the American Journal of Surgery. Sorry, your blog cannot share posts by email. Get the latest public health information from CDC: They noted that sugar water placed on a window- sill turned cloudy in the shade but remained clear while in the sun. The first treatment on a human took place in 1928 when a patient was determined to be in a moribund state after a septic abortion complicated by hemolytic streptococcus septicemia. How Does Ultraviolet Blood Irradiation Work? In 1922 another pioneer to experiment with Light Therapy was Kurt Naswitis who directly irradiated the blood with UV light through a shunt. Today we read all sorts of nonsense about the toxicy of blue light, but that’s artifical blue which as generated by LEDs or CFLs has a spectral curve of very “spikey” quality, and is not any true broad spectrum of blue or near UV as comes from the Sun. John Ott made a video “Exploring the Spectrum” which demonstrated these issues, that the natural sunlight with near-UV and blue frequencies were health-promoting, while dominantly red light lacking in the blues and UV was anti-health. One of the major obstacles that UBI has consistently faced throughout the almost 90 years since the first patient was treated has been the lack of understanding of the mechanisms of action. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: What is ultraviolet blood irradiation? The practice was originally developed in the United States, but most recent research on it has been conducted in Germany (by UV lamps) and in Russia (in all variants).  |  Emmett K Knott (Fig. Extracorporeal photopheresis: what is it and when should it be used? The exposure time per given unit of blood was approximately 10 s, at a peak wavelength of 253.7 nm (ultraviolet C) provided by a mercury quartz burner, and the blood was immediately re-perfused [7]. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Ultraviolet Blood Irradiation (UBI) is a procedure that exposes the blood to light to heighten the body’s immune response and to kill infections. She proceeded to give birth to two children. J Photochem Photobiol B. 25.1) in Seattle, WA reasoned that the beneficial effects of UV irradiation to the skin obtained by Ude, might (at least partly) be explained by the irradiation of blood circulating in the superficial capillaries of the skin. Will QFS Blockchain Encryption Code Technology Win It, Older PROM papers are now under the Publications menu. In 1801 Johann Wilhelm Ritter, a Polish physicist working at the University of Jena in Germany discovered a form of light beyond the violet end of the spectrum that he called “Chemical Rays” and which later became “Ultraviolet” light [1]. Using PCR Tests to Diagnose COVID19 Is Bad Science & Fraudulent, How Quicycle Is Advancing the Cause of Pure Science, Gone With The Wind: Power Shortages The ‘New Normal’, Fast Radio Burst in Milky Way Galaxy May Solve Space Mystery, Top Pfizer Whistleblower Trashes Company’s Vaccine ‘Breakthrough’ Spin, Joe Biden’s votes violate Benford’s Law (Mathematics), US Election Sting? suggested that some structural alterations in the erythrocytes, particularly in the glycocalyx were related to the improved effect of autotrans-fused blood after UV-irradiation [36].  |  Ultraviolet Blood Irradiation uses ultraviolet energy which is put into the body by way of IV to oxygenate the blood and is theorized to kill microbes in the body, among other things. 2012 Feb;10(2):185-95. doi: 10.1586/eri.11.166. PRINCIPIA SCIENTIFIC INTERNATIONAL is legally registered in the UK as a company incorporated for charitable purposes. Later studies were mostly performed by Russian workers and in other Eastern countries and the modern view in Western countries is that UBI remains highly controversial.This chapter discusses the potential of UBI as an alternative approach to current methods used to treat infections, as an immune-modulating therapy and as a method for normalizing blood parameters.