J AOAC Int 2008;91(2):383-386. Cerrutti, P. Alzamora S. Vanillin as an antimicrobial for producing shelf-stable strawberry puree. Faster acquisition of an olfactory discrimination following septal lesions in male albino rats. J Exp.Psychol Anim Behav.Process 1981;7(1):59-69. Vanilla extract produced by biotechnological methods of plant culturing have yielded good grades of natural vanilla. View abstract. Nielsen, P. V. and Rios, R. Inhibition of fungal growth on bread by volatile components from spices and herbs, and the possible application in active packaging, with special emphasis on mustard essential oil. Sobel, N., Prabhakaran, V., Hartley, C. A., Desmond, J. E., Zhao, Z., Glover, G. H., Gabrieli, J. D., and Sullivan, E. V. Odorant-induced and sniff-induced activation in the cerebellum of the human. Moore, and Vanilla pompon Scheide.]) At this time there is not enough scientific information to determine an appropriate range of doses for vanilla. Generally recognized as safe when used as food. Ann Bot. J Agric Food Chem 9-9-2009;57(17):7651-7658. Naturwissenschaften 2007;94(7):595-600. Naturwissenschaften 2007;94(7):595-600. View abstract. Goubet, N., Strasbaugh, K., and Chesney, J. J Sep.Sci 2009;32(20):3425-3431. Vanillin is also used in the fragrance industry, in perfumes, and to mask unpleasant odors or tastes in medicines, livestock fodder, and cleaning products. Ramaroson-Raonizafinimanana, B., Gaydou, E. M., and Bombarda, I. Long-chain gamma-pyrones in epicuticular wax of two vanilla bean species: V. fragrans and V. tahitensis. However, it was cocarcinogenic when being administered intraperitoneally at high concentrations. Vanilla is a plant. View abstract. Kettenmann, B., Jousmaki, V., Portin, K., Salmelin, R., Kobal, G., and Hari, R. Odorants activate the human superior temporal sulcus. Choochote, W., Chaithong, U., Kamsuk, K., Jitpakdi, A., Tippawangkosol, P., Tuetun, B., Champakaew, D., and Pitasawat, B. Repellent activity of selected essential oils against Aedes aegypti. J Agric Food Chem 2001;49(11):5161-5164. Survival of Listeria monocytogenes in vanilla-flavored soy and dairy products stored at 8 degrees C. J Food Prot. View abstract. Thompson, R. D. and Hoffmann, T. J. J Cereb.Blood Flow Metab 2004;24(6):677-680. Part 182 -- Substances Generally Recognized As Safe. J Neurochem. 2007;28(3):189-194. J Agric Food Chem 2000;48(9):3801-3805. Lucas, F. and Sclafani, A. Carbohydrate-conditioned odor preferences in rats. Clinical studies are lacking.Kumar 2000, Kumar 2004, Kamat 2000, Durant 2003, Gustafson 2000. Mutat.Res 12-1-2007;634(1-2):69-80. 1981;23(4):249-251. Choo, J. H., Rukayadi, Y., and Hwang, J. K. Inhibition of bacterial quorum sensing by vanilla extract. View abstract. 1989;103(1):47-52. So lab-produced vanillin is often used as a substitute for vanilla. View abstract. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. Feron, V. J., Til, H. P., de Vrijer, F., Woutersen, R. A., Cassee, F. R., and van Bladeren, P. J. Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment. View abstract. 2007;21(2):113-115. Trop.Med Int Health 2005;10(11):1190-1198. Ann Bot. View abstract. Keep in mind that natural products are not always necessarily safe and dosages can be important. Bourbon Vanilla, Common Vanilla, Madagascar Vanilla, Mexican Vanilla, Réunion Vanilla, Tahitian Vanilla, Tahiti Vanilla, Vainilla, Vanilla planifolia, Vanilla tahitensis, Vanille, Vanille Bourbon, Vanille de Bourbon, Vanille de Madagascar, Vanille du Mexique, Vanille de Tahiti, Vanillin. Determination of coumarin as an adulterant in vanilla flavoring products by high-performance liquid chromatography. J Hyg (Lond) 1984;93(2):377-380. de Tamsut, L. S. and Garcia, C. E. [Microbiological quality of vanilla ice cream manufactured in Caracas, Venezuela]. View abstract. View abstract. View abstract. View abstract. Durant, S. and Karran, P. Vanillins--a novel family of DNA-PK inhibitors. View abstract. We comply with the HONcode standard for trustworthy health information -. J Chromatogr. Brunschwig, C., Collard, F. X., Bianchini, J. P., and Raharivelomanana, P. Evaluation of chemical variability of cured vanilla beans (Vanilla tahitensis and Vanilla planifolia). View abstract. View abstract. Electroencephalogr.Clin.Neurophysiol. View abstract. Vanilla beans contain approximately 1% to 2% vanillin (4-hydroxy-3-methoxybenzaldehyde), the major flavor component. Arch Pharm Res 1999;22(4):404-409. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Funk, C. and Brodelius, P. E. Phenylpropanoid Metabolism in Suspension Cultures of Vanilla planifolia Andr. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Apoptosis. Fitzgerald, D. J., Stratford, M., Gasson, M. J., Ueckert, J., Bos, A., and Narbad, A. Mode of antimicrobial action of vanillin against Escherichia coli, Lactobacillus plantarum and Listeria innocua. Influence of irradiation procedure. In foods and beverages, vanilla is a well-known flavoring, but it is also added to foods to reduce the amount of sugar needed for sweetening. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Ali, L., Perfetti, G., and Diachenko, G. Rapid method for the determination of coumarin, vanillin, and ethyl vanillin in vanilla extract by reversed-phase liquid chromatography with ultraviolet detection. View abstract. Soothing effect of a familiar odor on full-term newborns. Information from this source is evidence-based and objective, and without commercial influence. View abstract. View abstract. Sharma, U. K., Sharma, N., Sinha, A. K., Kumar, N., and Gupta, A. P. Ultrafast UPLC-ESI-MS and HPLC with monolithic column for determination of principal flavor compounds in vanilla pods. Fitzgerald, D. J., Stratford, M., and Narbad, A. View abstract. Psychiatry Res 4-30-2010;176(2-3):190-196. View abstract. 2004;20(3):715-720. View abstract. : II. Percept.Psychophys. 5-15-2007;101(2):451-465. View abstract. Vet.Hum.Toxicol. J Agric Food Chem 9-9-2009;57(17):7651-7658. Beaudry, F., Ross, A., and Vachon, P. Development of a LC-ESI/MS/MS assay for the quantification of vanillin using a simple off-line dansyl chloride derivatization reaction to enhance signal intensity. Ho, K., Yazan, L. S., Ismail, N., and Ismail, M. Apoptosis and cell cycle arrest of human colorectal cancer cell line HT-29 induced by vanillin. Hail, N., Jr. Mechanisms of vanilloid-induced apoptosis. View abstract. View abstract. View abstract. View abstract. View abstract. Sullivan, G. Examination of Mexican vanilla extracts for coumarin adulteration: Part II. Sangsuwan, J., Rattanapanone, N., Auras, R. A., Harte, B. R., and Rachtanapun, P. Factors affecting migration of vanillin from chitosan/methyl cellulose films. Properties of diphenolase from Vanilla planifolia (Andr.) Physiol Behav. Odink, J., Korthals, H., and Knijff, J. H. Simultaneous determination of the major acidic metabolites of catecholamines and serotonin in urine by liquid chromatography with electrochemical detection after a one-step sample clean-up on Sephadex G-10; influence of vanilla and banana ingestion. Farthing, D., Sica, D., Abernathy, C., Fakhry, I., Roberts, J. D., Abraham, D. J., and Swerdlow, P. High-performance liquid chromatographic method for determination of vanillin and vanillic acid in human plasma, red blood cells and urine. Free Radic.Res Commun 1992;17(5):349-352. 2006;29(5):1167-1172. View abstract. What factors influenced or will influence your purchase? 2008;5(9):1762-1769. View abstract. Electroencephalogr.Clin.Neurophysiol. 1993;15(1):51-58. Mutat.Res. 7-18-2007;252(2):280-289. Fitzgerald, D. J., Stratford, M., and Narbad, A. A., Demarini, D. M., and Klein, C. B. Antimutagenicity of cinnamaldehyde and vanillin in human cells: Global gene expression and possible role of DNA damage and repair. Int J Oncol. View abstract. Odink, J., Korthals, H., and Knijff, J. H. Simultaneous determination of the major acidic metabolites of catecholamines and serotonin in urine by liquid chromatography with electrochemical detection after a one-step sample clean-up on Sephadex G-10; influence of vanilla and banana ingestion. Fitoterapia 2007;78(5):359-364. 2003;92(3):437-444. View abstract. View abstract. Appl.Microbiol Biotechnol 2001;57(5-6):725-730. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. View abstract. Pain, S. On the trail of Tahiti's elusive vanilla orchid. Mazza, D. S., O'Sullivan, M., and Grieco, M. H. HIV-1 infection complicated by food allergy and allergic gastroenteritis: a case report.