, DOI: assigned to this reactive group. Use descriptors are adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes described in Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment. Appl Environ Microbiol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. There are Rial D, Vázquez JA, Murado MA: Effects of three heavy metals on the bacteria growth kinetics: a bivariate model for toxicological assessment. 2008, 46: 2639-2647. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. The lack of significance in the lag phase was clear in the rest of bacteria. Strotmann UJ, Pagga U: A growth inhibition test with sewage bacteria -results of an international ring test 1995. At pre-established times, samples were centrifuged at 4,000 g for 15 min. When information is available in all sources, the first two are displayed as a priority. Cur Opin Biotechnol. The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. REACH regulation aims to improve the protection of human health and the environment from the risks that can be posed by chemicals. Furthermore, some substances can be found in an article, but with unlikely exposure (e.g. This substance has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about this substance from registration dossiers. Please upgrade your Internet Explorer to a newer version. Application to evaluation of 15 peptones for lactic acid bacteria productions. These microorganisms were chosen by their different features about cell wall structure (Gram-positive and negative), behaviour (free, opportunistic parasite, probiotic), habitats (marine and terrestrial) and metabolic properties (homo and heterofermentative). They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than mineral acids such as hydrochloric acid. The mathematical equations were robust and consistent (p-values < 0.001 from Fisher's F test), the residuals were randomly distributed and autocorrelations were not observed by Durbin-Watson test (data not shown). The studied bacteria are shown in Table 7. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners). Evaluation of the whole time course of observed effects using a toxicodynamic analysis would be a more interesting approach in characterizing the corresponding bacterial responses [2]. Springer Nature. CRC Press, Boca Raton, Fla. Bruno-Bárcena JM, Azcárate-Peril A, Hassan HH: Role of antioxidant enzymes in bacterial resistance to organic acids. in case of consumer and professional uses). machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners). This equation was also validated using relative population size [24] as growth response. Other release to the environment of this substance is likely to occur from: indoor use as processing aid. Significance of the parameters was always high and in all fermentations the toxicodynamic equation was statistically consistent and had good predictability.